Complete Genome Sequence of Streptomyces lavendulae subsp. lavendulae CCM 3239 (Formerly “ Streptomyces aureofaciens CCM 3239”), a Producer of the Angucycline-Type Antibiotic Auricin
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منابع مشابه
Complete Genome Sequence of Streptomyces lavendulae subsp. lavendulae CCM 3239 (Formerly “Streptomyces aureofaciens CCM 3239”), a Producer of the Angucycline-Type Antibiotic Auricin
Streptomyces lavendulae subsp. lavendulae CCM 3239 produces the angucycline antibiotic auricin and was thought to be the type strain of Streptomyces aureofaciens We report the complete genome sequence of this strain, which consists of a linear chromosome and the linear plasmid pSA3239, and demonstrate it to be S. lavendulae subsp. lavendulae.
متن کاملThe gene cluster aur1 for the angucycline antibiotic auricin is located on a large linear plasmid pSA3239 in Streptomyces aureofaciens CCM 3239.
We previously identified a polyketide synthase gene cluster, aur1, responsible for the production of the angucycline antibiotic auricin in Streptomyces aureofaciens CCM 3239. A sequence analysis of the aur1 flanking regions revealed the presence of several genes encoding proteins homologous to those for Streptomyces linear plasmid replication, partitioning and telomere-binding. Pulse-field gel ...
متن کاملA gene determining a new member of the SARP family contributes to transcription of genes for the synthesis of the angucycline polyketide auricin in Streptomyces aureofaciens CCM 3239.
Three regulators, Aur1P, Aur1R and a SARP-family Aur1PR3, have been previously found to control expression of the aur1 cluster for the angucycline antibiotic auricin in Streptomyces aureofaciens CCM 3239. Here, we describe an additional regulatory gene, aur1PR4, encoding a homologue from the SARP-family regulators. Its role in auricin regulation was confirmed by its disruption that dramatically...
متن کاملStreptomyces lavendulae and Streptomyces venezuelae.
With the growing economic significance of some Streptomyces species, the necessity of establishing their precise characteristies in well-defined specific terms becomes of great theoretical and practical importance (Waksman, 1957). The purpose of this paper is to present a comparative study of the main morphological, physiological, and biochemical characteristics of cultures belonging to the Str...
متن کاملStudies on Streptomyces lavendulae.
Since the isolation of streptothricin by Waksman and Woodruff in 1942 from a strain of Streptomyces lavendulae, numerous reports have appeared concerning the ability of different actinomycetes to produce this antibiotic or closely related compounds. In most of the antibiotic screening programs, streptothricin and streptothricinlike substances are among the first to be commonly encountered as pr...
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ژورنال
عنوان ژورنال: Genome Announcements
سال: 2018
ISSN: 2169-8287
DOI: 10.1128/genomea.00103-18